Pay in installments of $5.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 18 - Jul 23
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
APC Mouse Anti-Mouse CD45.1 Antibody (S-R521)Product Specification Host Mouse Antigen CD45R B220 Synonyms Receptor type tyrosine protein phosphatase C; Leukocyte common antigen (L CA); Lymphocyte antigen 5 (Ly 5); T200; CD45; Ly 5; Ptprc Location Cell membrane, Synapse Accession P06800 Clone Number S R521 Antibody Type Mouse mAb Isotype IgG2a,k Application FCM Reactivity Ms Positive Sample SJL mouse splenocytes Purification Protein A Concentration 0. 2 mg ml Conjugation APC Physical Appearance
Product Specification
| Host | Mouse |
| Antigen | CD45R/B220 |
| Synonyms | Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen (L-CA); Lymphocyte antigen 5 (Ly-5); T200; CD45; Ly-5; Ptprc |
| Location | Cell membrane, Synapse |
| Accession | P06800 |
| Clone Number | S-R521 |
| Antibody Type | Mouse mAb |
| Isotype | IgG2a,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | SJL mouse splenocytes |
| Purification | Protein A |
| Concentration | 0.2 mg/ml |
| Conjugation | APC |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD45.1 is a variant of CD45 (Leukocyte Common Antigen), a protein tyrosine phosphatase (PTP) family member with a molecular weight of approximately 180–240 kDa. It is broadly expressed on the surface of all hematopoietic cells except mature erythrocytes and platelets. Encoded by the Ptprca allele, CD45.1 differs in amino acid sequence from the more common CD45.2 (encoded by Ptprcb) and is primarily expressed in mouse strains such as SJL/J, RIII, STS/A, and DA. Functionally, CD45.1 plays a crucial role in immune cell signaling by modulating T-cell receptor (TCR) and B-cell receptor (BCR) pathways, thereby influencing cell activation, proliferation, and differentiation. Due to its differential expression compared to CD45.2, CD45.1 mouse models (e.g., B6-Ly5.1) are widely used in cell transplantation tracking experiments to distinguish donor and recipient cells. These models are valuable in tumor immunology, autoimmune disease research, and hematopoietic development studies.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy