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Description
AIFM2/FSP1 Recombinant Rabbit mAb (S-2271-67)Product Specification Host Rabbit Antigen AIFM2 FSP1 Synonyms Ferroptosis suppressor protein 1; Apoptosis inducing factor homologous mitochondrion associated inducer of death (AMID); p53 responsive gene 3 protein; AMID; PRG3 Immunogen Synthetic Peptide Location Cytoplasm, Nucleus, Mitochondrion, Cell membrane Accession Q9BRQ8 Clone Number S 2271 67 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms Positive Sample HeLa,
Product Specification
| Host | Rabbit |
| Antigen | AIFM2/FSP1 |
| Synonyms | Ferroptosis suppressor protein 1; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death (AMID); p53-responsive gene 3 protein; AMID; PRG3 |
| Immunogen | Synthetic Peptide |
| Location | Cytoplasm, Nucleus, Mitochondrion, Cell membrane |
| Accession | Q9BRQ8 |
| Clone Number | S-2271-67 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms |
| Positive Sample | HeLa, MCF7, A172, NIH/3T3, mouse kidney, mouse liver |
| Predicted Reactivity | Bv |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | Hu, Ms |
| IHC-P | 1:200 | Hu, Ms |
Background
AIFM2, also known as ferroptosis suppressor protein 1 (FSP1), apoptosis-inducing factor-homologous mitochondrion-associated inducer of death (AMID), or p53-responsive gene 3 (PRG3), is a protein encoded by the AIFM2 gene in humans. It is a flavoprotein oxidoreductase that plays a crucial role in regulating ferroptosis, a form of cell death characterized by iron-dependent lipid peroxidation. FSP1 primarily localizes to the plasma membrane and lipid droplets, and it suppresses ferroptosis by reducing ubiquinone (CoQ10) to ubiquinol (CoQ10-H2) using NAD(P)H as a cofactor, thereby preventing lipid peroxidation. This protein is also involved in the reduction of other molecules, such as vitamin K, and has been implicated in tumorigenesis and resistance to therapy in certain cancer models.
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4.0 ★★★★★
Based on 22 reviews
Sort
Product Reviews
★★★★★ 5
Beautiful angel statue
Size: 7*5*13 in, Size: 7*5*13 in
Got this angel garden statue about three weeks ago to put in our backyard and we really like how it looks. The resin construction is detailed and well-made, depicting an angel with spread wings and three-dimensional flowers adorning the hair, collar, and skirt hem. The craftsmanship is impressive for the price, gives off a soft romantic vibe. The solar panel on the back charges during the day - they claim 8 hours for a full charge which seems about right with good sun exposure. As night falls, the string lights embedded in the flowers turn on automatically which is convenient. However, the lights are not very bright at all. They emit a warm glow but it’s pretty dim, more of a subtle accent rather than actual illumination. You can see the flowers lit up but it’s not going to light up your garden or anything. The soft tranquil glow they advertise is accurate - it’s definitely tranquil because it’s so faint. Despite the dim lighting, we still like the overall appearance and ambiance it creates. The angel design is elegant and the natural elements blend nicely with our garden decor. The statue is weather-resistant and has held up fine through rain and sun exposure so far. The automatic on/off feature works reliably with the solar sensor. The energy efficiency is good since it’s completely solar powered with no wiring needed. Setup was easy, just stake it in the ground where it gets sunlight. The symbolism of angels and flowers is nice for memorial or decorative purposes. The size is decent, not huge but noticeable in the garden. The resin material feels durable. Would make a thoughtful gift for someone who appreciates garden decorations. Price seems reasonable for what you get. Would I recommend it? Yeah if you want a decorative angel statue with subtle accent lighting, just don’t expect bright illumination at night.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 24, 2026
★★★★★ 4
Very nice resin sculpture but LED distracting
Size: 7*5*13 in, Size: 7*5*13 in
I was pleasantly surprised at the quality of this resin Angel statue. It looks better, in person, than shown in pictures. The features of the face, and wings, are very nice.
What I found distracting/detracting from my overall favorable opinion is that the LED lights are embedded in the flowers at the waist and base. This is distracting at night as they do not illuminate the face or wings but leaves that in darkness with just bright lights around the waist and base. If the lights were higher up, or more directional, perhaps embedded in the wings to light up the face, torso and wings it would be so much better.
To use the solar lights at night, care should be taken to ensure the back is directed toward light and that nothing surrounds the statue to block proper charging, The solar panel in back is very small and will not provide much recharging unless in direct light. If placed on the ground, with plants around it, the panel will be shaded which is not efficient.
I am very pleased with the actual sculpture and would rate it higher but, I personally find the addition of the solar lights is superfluous, with no real additional value to an otherwise very nice sculpture. As a result, I intend to turn off the solar light and illuminate this with a garden light/spot.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 9, 2026
★★★★★ 5
Great Value, Lasts All Night
Size: 7*5*13 in
Impressed with the quality and performance. The angel is sturdy and weather-resistant. The solar panel charges efficiently even on partly cloudy days, and the LED light stays on from dusk until morning. It provides a lovely, gentle light that’s both decorative and functional. Excellent purchase for the price!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 8, 2026
★★★★★ 5
Beautiful angel statue
Size: 7*5*13 in, Size: 7*5*13 in
Got this angel garden statue about three weeks ago to put in our backyard and we really like how it looks. The resin construction is detailed and well-made, depicting an angel with spread wings and three-dimensional flowers adorning the hair, collar, and skirt hem. The craftsmanship is impressive for the price, gives off a soft romantic vibe. The solar panel on the back charges during the day - they claim 8 hours for a full charge which seems about right with good sun exposure. As night falls, the string lights embedded in the flowers turn on automatically which is convenient. However, the lights are not very bright at all. They emit a warm glow but it’s pretty dim, more of a subtle accent rather than actual illumination. You can see the flowers lit up but it’s not going to light up your garden or anything. The soft tranquil glow they advertise is accurate - it’s definitely tranquil because it’s so faint. Despite the dim lighting, we still like the overall appearance and ambiance it creates. The angel design is elegant and the natural elements blend nicely with our garden decor. The statue is weather-resistant and has held up fine through rain and sun exposure so far. The automatic on/off feature works reliably with the solar sensor. The energy efficiency is good since it’s completely solar powered with no wiring needed. Setup was easy, just stake it in the ground where it gets sunlight. The symbolism of angels and flowers is nice for memorial or decorative purposes. The size is decent, not huge but noticeable in the garden. The resin material feels durable. Would make a thoughtful gift for someone who appreciates garden decorations. Price seems reasonable for what you get. Would I recommend it? Yeah if you want a decorative angel statue with subtle accent lighting, just don’t expect bright illumination at night.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 24, 2026
★★★★★ 4
Very nice resin sculpture but LED distracting
Size: 7*5*13 in, Size: 7*5*13 in
I was pleasantly surprised at the quality of this resin Angel statue. It looks better, in person, than shown in pictures. The features of the face, and wings, are very nice.
What I found distracting/detracting from my overall favorable opinion is that the LED lights are embedded in the flowers at the waist and base. This is distracting at night as they do not illuminate the face or wings but leaves that in darkness with just bright lights around the waist and base. If the lights were higher up, or more directional, perhaps embedded in the wings to light up the face, torso and wings it would be so much better.
To use the solar lights at night, care should be taken to ensure the back is directed toward light and that nothing surrounds the statue to block proper charging, The solar panel in back is very small and will not provide much recharging unless in direct light. If placed on the ground, with plants around it, the panel will be shaded which is not efficient.
I am very pleased with the actual sculpture and would rate it higher but, I personally find the addition of the solar lights is superfluous, with no real additional value to an otherwise very nice sculpture. As a result, I intend to turn off the solar light and illuminate this with a garden light/spot.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 9, 2026